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KMID : 0616120090400040376
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Korean Journal of Pharmacognosy
2009 Volume.40 No. 4 p.376 ~ p.381
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Analysis of Quinic Acid Derivatives on Seven Cultivars of the Lettuce (Lactuca sativa L.) and Peroxynitrite Scavenging Effect
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Nugroho Agung
Jang Suk-Woo
Kim Won-Bae
Lee Kang-Ro
Choi Jae-Sue
Park Hee-Juhn
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Abstract
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The compositional analysis and the peroxynitrite (ONOO-) scavenging assay were undertaken to demonstrate beneficial
dietary effect of lettuce (Lactuca sativa L., Compositae). Quinic acid derivatives of the seven cultivars were qualitatively
and quantitatively analyzed by HPLC to lead to the finding of 3,4-di-O-caffeoyquinic acid and 3-O-p-coumaroylquinic acid and their contents ranged over 2.72-4.47 mg/g and 8.97-23.26 mg/g, respectively. A cultivar Hacheong had the highest quantity of quinic acid derivatives. The peroxynitrite scavenging effect of the five cultivars (Jangsu, Gosina 27, Gopung, Yeolpungjeogchima, and Mipungjeogchugmyeon) were ranged over 7.45-8.26μg/ml as IC50s while those of Hacheong and Mihong had less effect (IC50 >10 μg/ml).
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KEYWORD
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Lactuca sativa, Compositae, peroxynitrite, quinic acid, HPLC
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